Selected Publications
Evanchuk JL, Kozyrskyj A, Vaghef-Mehrabani E, Lamers Y, Giesbrecht GF, Letourneau N, Aghajafari F, Dewey D, Leung B, Bell RC, Field CJ (2024). Maternal iron and vitamin D status during the 2nd trimester is inversely associated with 3rd trimester depression symptoms among pregnant participants in the APrON cohort. The Journal of Nutrition 154(1):174-184. doi: 10.1016/j.tjnut.2023.10.029
Duarte-Guterman P, Richard JE, Lieblich SE, Eid RS, Lamers Y, Galea LAM (2023). Cellular and molecular signatures of motherhood in the adult and ageing rat brain. Open Biology 13: 230217. https://doi.org/10.1098/rsob.230217
Caffrey A, Lamers Y, Murphy MM, Letourneau N, Irwin RE, Pentieva K, Ward M, Tan A*, Rojas-Gómez A, Santos-Calderón LA, Canals-Sans J, Leung BMY, Bell R, Giesbrecht GF, Dewey D, Field CJ, Kobor M, Walsh CP, McNulty H (2023). Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement strategies. Nutrition Bulletin Feb 21. doi: 10.1111/nbu.12611.
Lamers Y (2022). Vitamin B12 requirements in older adults – increasing evidence substantiates the need to re-evaluate recommended amounts and dietary sources.
The Journal of Nutrition 152(11). Pages 2317-2318. doi: 10.1093/jn/nxac179 (featured as “Editor’s Choice” editorial in December 2022 and by ASN)
Jarrett J, McNulty H, Hughes CF, Pentieva K, Strain JJ, McCann A, McAnena L, Cunningham C, Molloy AM, Flynn A, Hopkins SM, Horigan G, O’Connor C, Walton J, McNulty BA, Gibney MJ, Lamers Y, Ward M (2022). Vitamin B6 and riboflavin, their metabolic interaction and relationship with MTHFR genotype, in adults aged 18-102 years.
The American Journal of Clinical Nutrition 116(6):1767-1778. doi: 10.1093/ajcn/nqac240.
Ondičová M, Irwin RE, Thursby SJ, Hilman L, Caffrey A, Cassidy T, McLaughlin M, Lees-Murdock DJ, Ward M, Murphy M, Lamers Y, Pentieva K, McNulty H, Walsh C (2022). Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms. Clinical Epigenetics 14(1):63. doi: 10.1186/s13148-022-01282-y
Qiu W, Go KA, Lamers Y, Galea LAM (2021). Postpartum corticosterone and fluoxetine shift the tryptophan-kynurenine pathway in dams. Psychoneuroendocrinology 130:105273. Pages 1–6. doi: 10.1016/j.psyneuen.2021.105273.
Williams BA, Mayer C, McCartney H, Devlin AM, Lamers Y, Vercauteren SM, Wu JK, Karakochuk CD (2021). Detectable unmetabolized folic acid and sufficient folate and vitamin B12 concentrations are evident in folic acid-supplemented Canadian children with sickle cell disease. Frontiers in Nutrition, Clinical Nutrition 8:1–7. doi: 10.3389/fnut.2021.64230
Tan A*, Sinclair G, Mattman A, Vallance HD, Lamers Y (2021). Maternal vitamin B12 status in early pregnancy and its association with birth outcomes in Canadian mother-newborn dyads. British Journal of Nutrition 126(12):1823–1831. doi.org/10.1017/S0007114521000581
Murphy MSQ, Muldoon KA, Sheyholislami H, Behan N, Lamers Y, Rybak N, Rennicks White R, Harvey ALJ, Gaudet LM, Smith GN, Walker MC, Wen SW, MacFarlane AJ (2021). Impact of high-dose folic acid supplementation in pregnancy on biomarkers of folate status and one-carbon metabolism: An ancillary study of the Folic Acid Clinical Trial (FACT).
The American Journal of Clinical Nutrition 113(5):1361–1371. https://doi.org/10.1093/ajcn/nqaa407
da Silva MT, Mujica‑Coopman MF*, Figueiredo ACC, Hampel D, Vieira LS, Farias DR, Shahab‑Ferdows S, Allen LH, Brito A, Lamers Y, Kac G, Vaz JS (2020). Maternal plasma folate concentration is positively associated with serum total cholesterol and low‑density lipoprotein across the three trimesters of pregnancy. Scientific Reports 10:20141. doi.org/10.1038/s41598-020-77231-7
Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field M, Finnell RH, Garza C, Green R, Gueant JL, Jacques PF, Johnston B, Klurfeld DM, Lamers Y, MacFarlane A, Miller JW, Molloy AM, O’Connor DL, Pfeiffer CM, Potischman NA, Rodricks JV, Rosenberg IH, Shane B, Selhub J, Ross SA, Stabler SP, Trasler J, Yamini S, Zappalà G (2020). Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop. The American Journal of Clinical Nutrition 112(5):1390–1403. doi: 10.1093/ajcn/nqaa259.
Qiu W, Duarte-Guterman P, Eid RS, Go KA, Lamers Y, Galea LAM (2020). Postpartum fluoxetine increases maternal hippocampal IL-1β 1 and decreased plasma tryptophan: clues for efficacy. Neuropharmacology, May 26, 2020. DOI: 10.1101/2020.02.22.960021
Plumptre L, Tammen S, Sohn KJ, Masih S, Visentin C, Aufreiter S, Malysheva O, Schroder TH*, Ly A, Berger H, Croxford R, Lamers Y, Caudill M, Choi SW, O’Connor DL, Kim YI (2020). Maternal and cord blood folate concentrations are inversely associated with fetal DNA hydroxymethylation, but not DNA methylation, in a cohort of pregnant Canadian women. Journal of Nutrition pii: nxz232. doi: 10.1093/jn/nxz232
Kvalsund M, Kayamba V, Kelly P, Birbeck GL, Mwansa-Thurman C, Nyeggen Sommer I, Lamers Y, Gardiner J, Herrmann DN (2020). Is folate deficiency a common cause of distal symmetric polyneuropathy in Zambian clinics? Journal of the Neurologic Sciences 409:116583. doi: 10.1016/j.jns.2019.116583.
Moukarzel S*, Wiedeman AM*, Soberanes LS, Dyer RA, Innis SM, Lamers Y (2019). Variability of Water-Soluble Forms of Choline Concentrations in Human Milk during Storage, after Pasteurization, and Among Women. (*shared first authorship). Nutrients 11(12). pii: E3024. doi: 10.3390/nu11123024.
Mujica-Coopman MF, Tan A, Schroder TH, Sinclair G, Vallance H, Lamers Y (2019). Serum betaine concentration is inversely associated with total homocysteine in early pregnancy independent of ethnicity while circulating betaine and dimethylglycine concentrations are significantly higher in South Asian compared to European pregnant women in Canada. Journal of Nutrition; pii: nxz178. doi: 10.1093/jn/nxz178
Brosnan J, Plumptre L, Brosnan ME, Pongnopparat T, Masih SP, Visentin CE, Berger H, Lamers Y, Caudill MA, Malysheva OV, O’Connor DL, Kim YI (2019). Formate concentrations in maternal plasma during pregnancy and in cord blood in a cohort of pregnant Canadian women: relationships to genetic polymorphisms and plasma metabolites. The American Journal of Clinical Nutrition 110(5):1131-1137. doi: 10.1093/ajcn/nqz152
Daniels L, Gibson RS, Diana A, Haszard JJ, Rahmannia S, Luftimas DE, Hampel D, Shahab-Ferdows S, Reid M, Melo L, Lamers Y, Allen LH, Houghton LA (2019). Micronutrient intakes of lactating mothers and their association with breast milk concentrations and micronutrient adequacy of exclusively breastfed Indonesian infants. The American Journal of Clinical Nutrition 110(2):391-400. doi: 10.1093/ajcn/nqz047.
Mujica-Coopman MF, Farias DR, Franco-Sena AB, Vaz J, Kac G, Lamers Y (2019). Maternal plasma pyridoxal 5’-phosphate concentration is inversely associated with plasma cystathionine concentration across all trimesters in healthy pregnant women.
Journal of Nutrition 149(8):1354-1362. doi: 10.1093/jn/nxz082
Schroder TH*, Tan A*, Sinclair G, Mattman A, Jung B, Vallance H, Lamers Y (2019). Reference intervals for serum total vitamin B-12 and holotranscobalamin concentrations and their change points with methylmalonic acid concentration to assess vitamin B-12 status during early and mid-pregnancy. (*shared first authorship). Clinical Chemistry and Laboratory Medicine May 14. pii: /j/cclm.ahead-of-print/cclm-2018-1337/cclm-2018-1337.xml. doi: 10.1515/cclm-2018-1337.
Lamers Y (2019). Approaches to improving micronutrient status assessment at the population level. Proceedings of the Nutrition Society Jan 15:1-7. doi: 10.1017/S0029665118002781
Kocyłowski R, Grzesiak M, Gaj Z, Lorenc W, Bakinowska E, Barałkiewicz D,von Kaisenberg C, Lamers Y, Suliburska J (2019). Association of the level of trace elements and minerals and folate in maternal serum and amniotic fluid with congenital abnormalities. Nutrients 11(2). pii: E328. doi: 10.3390/nu11020328
Suliburska J, Kocyłowski R, Grzesiak M, Gaj Z, Chan B, von Kaisenberg C, Lamers Y (2018). Evaluation of folate concentration in amniotic fluid and maternal and umbilical cord blood during labor. Archives of Medical Science. doi: 10.5114/aoms.2018.78776
Lamers Y, MacFarlane AJ, O’Connor DL, Fontaine-Bisson B (2018). Periconceptional intake of folic acid among low-risk women in Canada: summary of a workshop aiming to align prenatal folic acid supplement composition with current expert guidelines. The American Journal of Clinical Nutrition 108(6):1357-1368. doi: 10.1093/ajcn/nqy212.
Schroder TH, Sinclair G, Mattman A, Jung B, Barr SI, Vallance HD, Lamers Y (2017). Pregnant women of South Asian ethnicity in Canada have substantially lower vitamin B12 status compared with pregnant women of European ethnicity. British Journal of Nutrition 118 (6): 454-462. doi: 10.1017/S0007114517002331
Quay TAW, Frimer L, Janssen PA, Lamers Y (2017). Barriers and facilitators to recruitment of South Asians to health research: a scoping review. BMJ Open; 7(5):e014889. doi: 10.1136/bmjopen-2016-014889.
Jeruszka-Bielak M*, Isman C*, Schroder TH, Li W, Green TJ, Lamers Y (2017).
South Asian ethnicity is related to the highest risk of vitamin B12 deficiency in Canadian pregnant women. *shared first authorship. Nutrients 9; doi: 10.3390/nu9040317
Chebaya P, Karakochuk CD, March KM, Chen NN, Stamm RA, Koreun H, Sophonneary P, Borath M, Shahab-Ferdows S, Hampel D, Barr SI, Lamers Y, Hougthon LA, Allen LH, Green TJ, Whitfield K (2017).
Correlations between maternal, breast milk, and infant vitamin B12 concentrations among mother-infant dyads in Vancouver, Canada and Prey Veng, Cambodia: an exploratory analysis. Nutrients 9; doi: 10.3390/nu9030270
Mujica-Coopman MF, Franco-Sena AB, Farias DR, Vaz J, Brito A, Kac G, Lamers Y (2017).
Vitamin B6 status in unsupplemented pregnant women is associated positively with serum docosahexaenoic acid and inversely with the n-6-to-n-3 fatty acid ratio. Journal of Nutrition 147(2):170-178. doi: 10.3945/jn.116.239483.
Ho CL, Quay TAW, Devlin AM, Lamers Y (2016).
Prevalence and predictors of low vitamin B6 status in healthy young adult women in Metro Vancouver. Nutrients 8, 538; doi:10.3390/nu8090538
Schroder TH, Quay TAW, Mattman A, Sinclair G, Vallance H, Lamers Y (2016).
Reference interval of methylmalonic acid concentrations in dried blood spots of healthy, term newborns to facilitate neonatal screening of vitamin B12 deficiency. Journal of Clinical Biochemistry March 31 Epub ahead of print: doi: 10.1016/j.clinbiochem.2016.03.007
Cheong M, Xiao Y, Tay V, Karakochuk CD, Liu Y, Harvey S, Lamers Y, Houghton LA, Kitts DD, Green TJ (2016).
Folic acid fortified milk increases blood folate to concentrations associated with a very low risk of neural tube defects in Singaporean women of childbearing age. Asia Pacific Journal of Clinical Nutrition 25(1):62-70
Quay TAW, Schroder TH, Jeruszka-Bielak M, Li W, Devlin AM, Barr SI, Lamers Y (2015).
High prevalence of suboptimal vitamin B12 status in young adult women of South Asian and European ethnicity. Applied Physiology, Nutrition, and Metabolism DOI:10.1139/apnm-2015-0200
Karakochuk CD, Whitfield KC, Barr SI, Lamers Y, Devlin AM, Vercauteren SM, Kroeun H, Talukder A, McLean J, Green TJ (2015).
Genetic hemoglobin disorders rather than iron deficiency are a major predictor of hemoglobin concentration in women of reproductive age in rural Prey Veng, Cambodia. Journal of Nutrition 145(1):134-42
Schroder TH, Quay TAW, Lamers Y (2014).
Methylmalonic acid quantified in dried blood spots provides a precise, valid, and stable measure of functional vitamin B-12 status in healthy women. Journal of Nutrition 2014, 144(10):1658-63
da Silva VR, Rios-Avila L, Lamers Y, Ralat MA, Midttun Ø, Quinlivan EP, Garrett TJ, Coats B, Shankar MN, Percival SS, Chi YY, Muller KE, Ueland PM, Stacpoole PW, Gregory JF (2013).
Metabolite profile analysis reveals functional effects of vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women. Journal of Nutrition 2013,143(11):1719-27
Gregory JF, Park Y, Lamers Y, Bandyopadhyay N, Chi YY, Lee K, Kim S, da Silva V, Hove N, Ranka S, Kahveci T, Muller K, Stevens R, Newgard C, Stacpoole P, Jones D (2013).
Metabolomic Analysis Reveals Extended Metabolic Consequences of Marginal Vitamin B-6 Deficiency in Healthy Human Subjects. Public Library of Science (PLoS) One 2013, 8(6):e63544
Yaremco E, Inglis A, Innis S, Hippman C, Carrion P, Lamers Y, Honer WG, Austin J (2013).
Red blood cell folate concentrations in pregnant women with mood disorders: A case series. Birth Defects Research Part A: Clinical and Molecular Teratology 2013, 97(6):416-20
Zhao M, Lamers Y, Ralat MA, Coats BS, Chi YY, Muller KE, Bain JR, Shankar MN, Newgard CB, Stacpoole PW, Gregory JF (2012).
Marginal vitamin B-6 deficiency decreases plasma n-3 and n-6 polyunsaturated fatty acid concentrations in healthy men and women. Journal of Nutrition 2012, 142(10): 1791-1797
Lamers Y (2011).
Folate recommendations for pregnancy, lactation, and infancy. Annals of Nutrition and Metabolism 2011, 59(1): 32-37
Lamers Y (2011).
Indicators and methods for folate, vitamin B-12, and vitamin B-6 status assessment in humans. Current Opinion in Clinical Nutrition and Metabolic Care 2011, 14(5): 445-54
Chi YY, Gribbin M, Lamers Y, Gregory JF, Muller KE (2011).
Global hypothesis testing for high dimensional repeated measures outcomes. Statistics in Medicine 2011. DOI: 10.1002/sim.4435
Lamers Y,Coats B, Ralat M, Quinlivan EP, Stacpoole PW, Gregory JF (2011).
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women. Journal of Nutrition 2011, 141(5): 835-42
Book Chapters
Gregory JF, da Silva V, Lamers Y (2009).
Kinetics of folate and one-carbon metabolism. In: Folate in Health and Disease. Pages 491-516. Editor: Bailey LB. 2nd Edition. Taylor and Francis Group, Florida.